When Magaña was five, she lived in the streets of Los Angeles with her mother who was addicted to heroin. She slept in back alleys and ate out of garbage cans. Eventually her grandparents gained custody, but Magaña was already scarred with the issues she'd experienced. Her mother overdosed and died when Magaña turned 17. Magana's father is a Mexican national who was deported to Mexico when she was a child. At the age of 14 she was raped by the father of some children that she babysat for while the children's mother watched. The man was convicted for the crime and served 10 years of a 14-year sentence, while the wife was not charged with any crime.
In 2007 Magaña broke her back by falling down three stories of stairs. She has suffered two auto accidents, one of which put her in a coma for several days.
Magaña started her MMA career on March 23, 2007 at Gladiator Challenge 60 against Tia Castillo. She won via TKO in the first round.
She suffered her first defeat when she tapped out to an armbar by Jessica Aguilar.
In April 2019, Magaña was left in an unresponsive coma after complications following spinal surgery at University Hospital in San Juan, Puerto Rico.
Two days later she woke up from her coma.